The Making of Medical Manuals: The 'Questions and Answers' Format in Ḥunayn Ibn Isḥāq’s Medical Manuals


Medical Student, King's College London
Ḥunayn Ibn Isḥāq: a Medieval Arab scholar who transformed his understanding of ancient Greek medical texts into manuals for the benefit of many successive generations of students.

The knowledge demanded of medical students in the medieval period was more complex and comprehensive than one may imagine. There already existed a complex system of disease classification including causation, presentation and treatment, with which every medical student was expected to be intimately familiar. Fortunately, over the course of centuries, sympathetic scholars had produced manuals containing information necessary for students to pass examinations and embark upon a successful career.

Title page from Ḥunayn’s Isagoge or Questions on Medicine. Arundel Or. 10, f. 28r
Title page from Ḥunayn’s Isagoge or Questions on Medicine. Arundel Or. 10, f. 28r

The great Syriac physician and prolific, multilingual translator Ḥunayn Ibn Isḥāq (AD 809–873) undertook the writing of two such manuals, motivated perhaps by the memory of his own expulsion from medical school for asking too many questions. Thereafter he travelled, probably to Alexandria, where he may have found answers to his questions in the works of Aristotle and Galen.

The 'Questions and Answers' Format

Ḥunayn subsequently wrote two manuals in the format of 'questions and answers'. The first, Questions on Medicine (Masā’il fī al-ṭibb), served as a general introduction to the subject and the second, Questions on the Eye (Masā’il fī al-‘ayn), dealt specifically with the anatomy and diseases of the eye. This format was rooted in Aristotelian logic and developed through a long series of Christian and Jewish religious disputations. A rich literature of debates between the various Christian theological schools and converts to Islam had developed, and this format was later taken up by early Muslim scholars. Islamic discussions initially dealt with interpretation of Quranic verses, but were soon applied to legal and scientific issues. The objective was both dialectic and didactic: the discussions were aimed at generally advancing knowledge and transmitting it to students. The 'questions and answers' format therefore fulfilled a practical function and provided an ideal template for teaching manuals in legal and medical disciplines.


Title page from Ḥunayn’s Questions on the Eye. Or. 6888, f. 1r
Title page from Ḥunayn’s Questions on the Eye. Or. 6888, f. 1r

Ḥunayn’s Method

Ḥunayn’s manuals represent a great advance toward classification, based on the classical theory of the four bodily humours. Some of his answers are remarkable for their descriptive precision and clarity of presentation. For example, in the Questions on Medicine, Ḥunayn posed the questions ‘how many types of fever are there?…What are they?’ and answered by distinguishing different origins, causes and patterns of febrile episodes (the cycles of bouts and crises in a fever). He also highlighted the importance of determining whether the cause of infection was exogenous (externally caused) or endogenous (internally caused); ‘for there are [fevers] that appear with a cause that occurs in some part of the body, and there are those that appear without a cause in any part of the body’.

Some of the questions and answers may appear surprising today. For example, in the Questions on the Eye Ḥunayn asks ‘why does the eye have two eyelids, instead of one or three?’ and answers that ‘the reason is if the eye had only one eyelid this eyelid could only originate from above or below; if its origin were from above, mineral collyrium would not stay in the eye...and in addition the eye would be uglier. If the lid were to originate from below, it would not cover the eye entirely...and the eye would furthermore have an ugly and disgusting appearance when open’. Since for Ḥunayn and his contemporaries the perfection of God's creation could not be doubted, his answer effectively excluded the possibility of humans having only one eyelid; this constituted a reductio ad absurdum, a classical argumentative device used in 'questions and answers' texts.


Ḥunayn’s discussion of the reason why the eye has two lids in his Questions on the Eye. Or. 6888, f. 5v
Ḥunayn’s discussion of the reason why the eye has two lids in his Questions on the Eye. Or. 6888, f. 5v

The Fate and Influence of Ḥunayn's Medical Manuals: East and West

The two manuals were extremely popular among medical students and soon constituted an indispensable revision tool. Senior physicians recognised their quality and they became standard examination materials for medical students across the medieval Arab world. In some manuscript copies of these texts, one can still read the certificates (ijāzahs) that were issued to their owners upon successfully passing their exams. These certificates allowed their bearers to practice the medical profession and may be considered precursors of our modern diplomas.

The success of Ḥunayn's manuals led to material from Questions on Medicine being translated into Latin probably as early as the eleventh century. In a straight narrative format, this material found its way into the Articella, a collection of six books considered to be the first medical curriculum in Medieval Europe. Ḥunayn became ‘Johannitius’ in Latin, and the text was referred to as the Isagoge ('Introduction'), as it is in some manuscripts of the Arabic text. Adopted by the Scuola Salernitana in Southern Italy, possibly the first medical school in Europe, the text was later introduced into England, probably by Anselm of Canterbury (died 1109). The manual was studied in Europe’s leading medical schools and universities in Paris, Bologna, Oxford, Montpellier, and Padua, and was continuously reprinted until the sixteenth century. As the Renaissance witnessed new developments in anatomy and physiology, Hunayn's manuals were gradually abandoned in European Universities. They had, nevertheless, succeeded in assisting many generations of medical students.

Primary Sources

  • Ḥunayn ibn Isḥāq, al-Masā’il fī al-ṭibb lil-muta‘allimīn, ed. by Muḥammad ‘Alī Abū Rayyān, Mursī Muḥammad ‘Arab and Jallāl Muḥammad Mūsá (al-Iskandarīyah: Dār al-Jāmi‘āt al-Maṣrīyah, 1987)
  • Jan E. Wilson and Samuel Dinkha, Hunayn ibn Ishaq's 'Questions on Medicine for Students': Transcription and Translation of the Oldest Extant Syriac Version (Vat. Syr. 192) (Vatican City: Biblioteca Apostolica Vaticana, 2010)
  • Paul Ghalioungui and Galal M. Moussa, 'Questions on Medicine for Scholars' by Hụnayn ibn Ishạ̄q; Translated into English, with a Preface and Historical Note, by Paul Ghalioungui, from a Critical Edition by Galal M. Moussa, of the Ninth Century Arabic Text, 'al Masaʼil fi al-tibb lil mutaʼallimin' (Cairo: A R E Al-Ahram Center for Scientific Translations, 1980)
  • Paul Sbath and Max Meyerhof, Le Livre des Questions sur l’Ooeil de Honain Ibn Ishaq (Cairo: Institut Français d'Archéologie Orientale, 1938)
  • Ḥunayn ibn Isḥāq al-‘Ibādī, Kitāb fī al-‘ayn mi’atān wa-sab‘ masā’il (London, British Library, Or. 6888)

Secondary Sources

  • Danielle Jacquart, 'A l'Aube de la Renaissance Médicale des XIe-XIIe Siècles: l' 'Isagoge Johannitii' et son Traducteur', Bibliothèque de l'Ecole des Chartes, 144 (1986), 209-240
  • Mark D. Jordan, 'Medicine as Science in the Early Commentaries on 'Johannitius'', Traditio 43 (1987), 121-145
  • Peter E. Pormann and Emily Savage-Smith, Medieval Islamic Medicine (Edinburgh: Edinburgh University Press, 2007), p. 25, p. 68
  • Ursula Weisser, 'Noch einmal zur Isagoge des Johannicius: Die Herkunft des Lateinischen Lehrtextes', Sudhoffs Archiv 70 (1986), 229-235